Indication:

Sitaglip-M is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both Sitagliptin and Metformin is appropriate.

Dosage & Administration:

Dose of this combination should be individualized on the basis of the patient’s current regimen, effectiveness, and tolerability while not exceeding the maximum recommended daily dose of 100 mg Sitagliptin and 2000 mg Metformin.
Administer once daily with meal preferably in the evening. Gradually escalate the dose to reduce the gastrointestinal side effects due to Metformin. May adjust the dosing based on effectiveness & tolerability while not exceeding the maximum daily dose of 100 mg Sitagliptin& and 2000 mg Metformin. Maintain the same total daily dose when changing between Sitaglip-M®50/500 &Sitaglip-M® 50/1000 without exceeding the maximum recommended daily dose of 2000 mg Metformin. Patients using two Sitaglip-M® tablets (such as two Sitaglip-M® 50/500 or two Sitaglip-M 50/1000 tablets) should take the two tablets together once daily. 100 mg Sitagliptin/2000 mg Metformin HCl XR tablets should be taken once daily.

Preparation:

Sitaglip-M® 50/500 Tablet: Each box contains 10 x 10 tablets in blister pack.
Sitaglip-M 50/850 Tablet: Each box contains 10 x 10 tablets in blister pack.
Sitaglip-M® 50/1000 Tablet: Each box contains 10 x 10 tablets in blister pack.