Indication:

Diacerein is an anthraquinone derivative which has moderate anti-inflammatory activity. It is anti-inflammatory at high doses and devoid of any irritant effect on the stomach.Action onset is slow, beginning towards day 30 of treatment and becoming significant after about 45 days. It has an additive effect in combination with NSAIDs.In vitro, diacerein has the following properties:
• Inhibition of phagocytosis and macrophage migration
• Inhibition of interleukin-1 synthesis
• Reduction of collagenolytic activity

Diacerein stimulates production of proteoglycans, glycosaminoglycans and hyaluronic acid. A positive effect on cartilage has been demonstrated in a number of researches.
Topcerin is used to relief functional symptoms & signs of osteoarthritis

Dosage & Administration:

Adults (15 yaers& more): 50mg BD should be taken during meal with a glass of water.

Preparation:

Topcerin^®-50 Capsule: Box containing 10 x 10 Capsules in alu-alublister pack.