Tafine®


Terbinafine HCL

Fungicides (Topical Preparations)



Indication:

Tablets: Fungal infections of the skin, hair and nails caused by dermatophytes such as trichophyton (e.g. T. rubrum, T. mentagrophytes, T. verrucosum, T. tonsurans, T. violaceum), Microsporum canis and Epiderphyton floccosum.
Oral Tafine® is indicated in the treatment of ringworm (tinea corporis, tinea cruris, tinea pedis and tinea capitis) and yeast infections of the skin caused by the genus Candida (e.g. Candida albicans) where oral therapy is considered appropriate owing to the site, severity or extent of the infection, Onychomycosis (fungal infection of the nail) caused by dermatophyte fungi.
Note: In contrast to topical Tafine®, oral Tafine® is not effective in pityriasis versicolor.

Cream: Fungal infection of the skin caused by dermatophytes such as Trichophyton (e.g. T. rubrum, T. mentagrophytes, T. verrucosum, T. violaceum), Microsporum canis and Epiderphyton floccosum. Yeast infections of the skin, principally those caused by the genus Candida (e.g. Candida albicans) Pityriasis (tinea) versicolor due to Pityrosporum orbiculare (also known as Malassezia furfur).


Dosage & Administration:

TABLETS
Children: No Data are available in children under two years of age (usually< 12kg.)
Children weighing < 20kg / 62.5 mg once daily
Children weighing 20-40kg / 125 mg once daily
Children weighing >40kg / 250 mg once daily
Adults: 250 mg once daily

CREAM
Tafine® can be applied once or twice daily. Cleanse and dry affected areas thoroughly before treating with Tafine®. Apply the cream to the affected skin and surrounding area in a thin layer and rub lightly. In the case of intertriginous infection (submammary, interdigital, intergluteal, inguinal) the application may be covered gauze, especially at night.


Preparation:

Tafine® 1% Cream: Tube containing 15 gm cream. Tafine® 250 Tablet: Box containing 10 x 10 tablets in blister pack.